BDBM50260924 CHEMBL4104344

SMILES Cc1ccc(cc1)-c1cnc(N)c(c1)-c1cnn(C)c1

InChI Key InChIKey=JBNFPUPGGQWNBG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260924   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50260924(CHEMBL4104344)Copy SMILESCopy InChI

Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant human LRRK2 (970 to 2527 residues) G2019S mutant expressed in baculovirus preincubated for 30 mins followed by fluorescein-...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50260924(CHEMBL4104344)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL