BDBM50260990 CHEMBL4087451

SMILES CN(CCn1cc(cn1)-c1ccc(F)cn1)C(=O)c1cc(C)ccc1-n1nccn1

InChI Key InChIKey=WQFVGTASYSVBKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260990   

TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260990(CHEMBL4087451)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260990(CHEMBL4087451)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed