BDBM50261322 CHEMBL4060424

SMILES Cc1cc(Cl)cc(c1)C(=O)N1CCc2oc(nc2C1)-c1ccc(F)cn1

InChI Key InChIKey=NMKCKZQPMUTSIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261322   

TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261322(CHEMBL4060424)
Affinity DataIC50: 46nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed