BDBM50261806 CHEMBL4078609

SMILES NC(=O)c1cc(Cl)c2c(Cl)c(n(C3CCCNC3)c2n1)C(F)(F)F

InChI Key InChIKey=JNBVAICFZXTBFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261806   

TargetSerine/threonine-protein kinase pim-2(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261806(CHEMBL4078609)
Affinity DataIC50: 25nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261806(CHEMBL4078609)
Affinity DataIC50: 67nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2020
Entry Details Article
PubMed