BDBM50261974 3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[3-trifluoromethylphenyl]thiourea::CHEMBL512966

SMILES CC(C)(C)c1ccc(cc1)-c1noc(n1)C(=O)NNC(=S)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=CBJKKUZKXZJCFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261974   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50261974(3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbon...)
Affinity DataIC50: 1.92E+5nMAssay Description:Inhibition of human SIRT1 assessed as nicotinamide releasing by microplate filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50261974(3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbon...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human SIRT2 assessed as nicotinamide releasing by microplate filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed