BDBM50261975 2-(3-(4-tert-butylphenyl)-1,2,4-oxadiazole-5-carbonyl)-N-(4-(trifluoromethyl)phenyl)hydrazinecarbothioamide::3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[4-trifluoromethylphenyl]thiourea::CHEMBL466960

SMILES CC(C)(C)c1ccc(cc1)-c1noc(n1)C(=O)NNC(=S)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=NTQRKGUDNORNMZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261975   

TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50261975(2-(3-(4-tert-butylphenyl)-1,2,4-oxadiazole-5-carbo...)
Affinity DataKi:  380nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as cleavage of MAPKK by fluorescence peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50261975(2-(3-(4-tert-butylphenyl)-1,2,4-oxadiazole-5-carbo...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as cleavage of MAPKK by fluorescence peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50261975(2-(3-(4-tert-butylphenyl)-1,2,4-oxadiazole-5-carbo...)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of human SIRT2 assessed as nicotinamide releasing by microplate filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50261975(2-(3-(4-tert-butylphenyl)-1,2,4-oxadiazole-5-carbo...)
Affinity DataIC50: 3.25E+5nMAssay Description:Inhibition of human SIRT1 assessed as nicotinamide releasing by microplate filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed