BDBM50262016 4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline::CHEMBL511563
SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12
InChI Key InChIKey=FAOGJKJCGFIFLI-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50262016
Affinity DataIC50: 55nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair