BDBM50262085 CHEMBL468397::methyl 5-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)-2-(4-bromophenyl)-2-isopropylpentanoate

SMILES COC(=O)C(CCCN(C)CCCc1nc2ccccc2[nH]1)(C(C)C)c1ccc(Br)cc1

InChI Key InChIKey=DUAKQKCVTZFHSD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262085   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50262085(methyl 5-((3-(1H-benzo[d]imidazol-2-yl)propyl)(met...)
Affinity DataIC50: 8.17nMAssay Description:Antagonist activity at T type calcium channel alpha1G expressed in HEK293 cells assessed as inhibition of peak currents at 1 uM by whole-cell patch-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50262085(methyl 5-((3-(1H-benzo[d]imidazol-2-yl)propyl)(met...)
Affinity DataIC50: 8.17nMAssay Description:Antagonist activity at T type calcium channel alpha1G expressed in HEK293 cells assessed as inhibition of peak currents by whole-cell patch-clamp met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50262085(methyl 5-((3-(1H-benzo[d]imidazol-2-yl)propyl)(met...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of T-type calcium channel subunit alpha-1G (unknown origin) expressed in HEK293 cells assessed as inactivation of channel current at holdi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50262085(methyl 5-((3-(1H-benzo[d]imidazol-2-yl)propyl)(met...)
Affinity DataIC50: 178nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50262085(methyl 5-((3-(1H-benzo[d]imidazol-2-yl)propyl)(met...)
Affinity DataIC50: 178nMAssay Description:Inhibition of human ERG by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed