BDBM50262256 CHEMBL4068975

SMILES NC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NCc1cc(F)ccc1F

InChI Key InChIKey=KKHYJYDEGGYOIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262256   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50262256(CHEMBL4068975)
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK3 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50262256(CHEMBL4068975)
Affinity DataIC50: 180nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluorescent labelled IPTSPITTTYFFFKKK peptide as substrate after 60 mins by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed