BDBM50262327 4-(5-(5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl)pyrazin-2-yl)-3-methylbenzonitrile::CHEMBL469005

SMILES COCc1nnc(-c2cnc(cn2)-c2ccc(cc2C)C#N)n1-c1ccc(OC)nc1

InChI Key InChIKey=YROLZLACGLYWCR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262327   

TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262327(4-(5-(5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-...)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262327(4-(5-(5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-...)
Affinity DataKi:  4.30E+3nMAssay Description:Antagonist activity at vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262327(4-(5-(5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed