BDBM50262339 11-Amino-12-(4-fluoro-phenyl)-3,3-dimethyl-3,4,5,7,8,9,10,12-octahydro-2H-dibenzo[b,g][1,8]naphthyridin-1-one::CHEMBL468000

SMILES CC1(C)CC(=O)C2C(c3ccc(F)cc3)c3c(N)c4CCCCc4nc3N=C2C1

InChI Key InChIKey=XPKDUOSYAVSWLD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262339   

TargetAcetylcholinesterase(Electric eel)
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262339(11-Amino-12-(4-fluoro-phenyl)-3,3-dimethyl-3,4,5,7...)
Affinity DataKi:  106nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262339(11-Amino-12-(4-fluoro-phenyl)-3,3-dimethyl-3,4,5,7...)
Affinity DataIC50: 540nMAssay Description:Inhibition of Electrophorus electricus AChE by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262339(11-Amino-12-(4-fluoro-phenyl)-3,3-dimethyl-3,4,5,7...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262339(11-Amino-12-(4-fluoro-phenyl)-3,3-dimethyl-3,4,5,7...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed