BDBM50262487 3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl)phenoxy)-5-fluorobenzonitrile::CHEMBL477145

SMILES Cc1cc(Cc2ccc(Cl)c(Oc3cc(F)cc(c3)C#N)c2F)n[nH]c1=O

InChI Key InChIKey=IUUQWNJIQOXGIC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262487   

TargetCytochrome P450 2C9(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed