BDBM50262598 2,4-Diamino-5-propyl-6-(2',6'-dimethylphenylsulfanyl)-7Hpyrrolo[2,3-d] pyrimidine::CHEMBL477789

SMILES CCCc1c(Sc2c(C)cccc2C)[nH]c2nc(N)nc(N)c12

InChI Key InChIKey=NNGNKQIKCOBEOX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262598   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262598(2,4-Diamino-5-propyl-6-(2',6'-dimethylphenylsulfan...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262598(2,4-Diamino-5-propyl-6-(2',6'-dimethylphenylsulfan...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262598(2,4-Diamino-5-propyl-6-(2',6'-dimethylphenylsulfan...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262598(2,4-Diamino-5-propyl-6-(2',6'-dimethylphenylsulfan...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed