BDBM50262620 CHEMBL476941::N-Biphenyl-2-ylmethyl-3-methyl-N-(S)-pyrrolidin-3-yl-butyramide

SMILES CC(C)CC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1

InChI Key InChIKey=RDLDWTPNWMTWKO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262620   

LigandPNGBDBM50262620(N-Biphenyl-2-ylmethyl-3-methyl-N-(S)-pyrrolidin-3-...)
Affinity DataKi:  30nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262620(N-Biphenyl-2-ylmethyl-3-methyl-N-(S)-pyrrolidin-3-...)
Affinity DataKi:  415nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed