BDBM50262624 CHEMBL477148::Pyrrolidine-1-carboxylic acid biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amide

SMILES O=C(N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1)N1CCCC1

InChI Key InChIKey=PMNGGGSGAMTCOG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262624   

LigandPNGBDBM50262624(Pyrrolidine-1-carboxylic acid biphenyl-2-ylmethyl-...)
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262624(Pyrrolidine-1-carboxylic acid biphenyl-2-ylmethyl-...)
Affinity DataKi:  4.19E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed