BDBM50262661 CHEMBL4075825

SMILES CN1c2ccccc2C(c2ccccc12)n1cncn1

InChI Key InChIKey=HAFYMZVHLNXUIY-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262661   

TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50262661(CHEMBL4075825)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50262661(CHEMBL4075825)
Affinity DataIC50: 810nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50262661(CHEMBL4075825)
Affinity DataKi:  3.34E+3nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50262661(CHEMBL4075825)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50262661(CHEMBL4075825)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed