BDBM50262676 (S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobutyramide::CHEMBL478833

SMILES CC(C)C(=O)N(Cc1ccccc1Oc1ccccc1)[C@H]1CCNC1

InChI Key InChIKey=JNLWAWMHYQYRKA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262676   

LigandPNGBDBM50262676((S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobuty...)
Affinity DataKi:  34nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262676((S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobuty...)
Affinity DataKi:  229nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262676((S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobuty...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed