BDBM50262725 Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine::CHEMBL478836

SMILES C(N[C@H]1CCNC1)c1ccccc1-c1ccccc1

InChI Key InChIKey=DGKNIGATLZIOSX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262725   

LigandPNGBDBM50262725(Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine | CH...)
Affinity DataKi:  271nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262725(Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine | CH...)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262725(Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine | CH...)
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed