BDBM50262731 (S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-carbamic acid ethyl ester::CHEMBL516730

SMILES CCOC(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1

InChI Key InChIKey=FFJNDOUWRPDJJX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262731   

LigandPNGBDBM50262731((S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-car...)
Affinity DataKi:  46nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262731((S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-car...)
Affinity DataKi:  427nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262731((S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-car...)
Affinity DataKi:  3.21E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed