BDBM50263349 1-(6-aminopyrimidin-4-yl)-N-mesityl-1H-benzo[d]imidazol-2-amine::CHEMBL477613

SMILES Cc1cc(C)c(Nc2nc3ccccc3n2-c2cc(N)ncn2)c(C)c1

InChI Key InChIKey=ZPRJXZVPSKFXMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263349   

TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263349(1-(6-aminopyrimidin-4-yl)-N-mesityl-1H-benzo[d]imi...)
Affinity DataIC50: 583nMAssay Description:Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263349(1-(6-aminopyrimidin-4-yl)-N-mesityl-1H-benzo[d]imi...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed