BDBM50263531 CHEMBL476146::N4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(2H-tetrazol-5-yl)-N2-(2-(thiophen-2-yl)ethyl)pyrimidine-2,4-diamine

SMILES C(Cc1cccs1)Nc1ncc(-c2nnn[nH]2)c(Nc2ccc3OCCOc3c2)n1

InChI Key InChIKey=BBTKUDMPZSPCOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263531   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263531(CHEMBL476146 | N4-(2,3-dihydrobenzo[b][1,4]dioxin-...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed