BDBM50263565 1-(pyridin-2-ylsulfonyl)-1,5,6,7,8,9-hexahydroazepino[4,5-f]indole::CHEMBL477387

SMILES O=S(=O)(c1ccccn1)n1ccc2cc3CCNCCc3cc12

InChI Key InChIKey=HQMMZOJQYXBMCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263565   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263565(1-(pyridin-2-ylsulfonyl)-1,5,6,7,8,9-hexahydroazep...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human CYP3A4 by microtiter plate assays using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263565(1-(pyridin-2-ylsulfonyl)-1,5,6,7,8,9-hexahydroazep...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human CYP3A4 by microtiter plate assays using PPR substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed