BDBM50263606 CHEMBL4100863

SMILES FC(F)(F)Oc1ccc(C[C@H](NC(=O)c2cnn(n2)C2CC(F)(F)C2)C(=O)NC2(CC2)C#N)cc1Cl

InChI Key InChIKey=VCKVRMZTLPAQME-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263606   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263606(CHEMBL4100863)
Affinity DataKi:  41nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263606(CHEMBL4100863)
Affinity DataKi:  76nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed