BDBM50263729 CHEMBL4074273

SMILES CC(=O)NCC1CN(c2ccccc2)c2ccccc2C1

InChI Key InChIKey=AOXKKYWKHVTVPY-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50263729   

TargetMelatonin receptor type 1B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataKi:  0.300nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT2 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataKi:  0.300nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT2 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataKi:  0.780nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT2 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataKi:  1.58nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataKi:  2.40nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataKi:  2.40nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed