BDBM50263888 CHEMBL491209::Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl)-1,4'-bipiperidine-1'-carboxylate

SMILES CCOC(=O)N1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key InChIKey=VBYGBDXPFRYDEZ-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263888   

TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263888(Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263888(Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl...)
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263888(Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl...)
Affinity DataEC50:  11.9nMAssay Description:Agonist activity at muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263888(Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl...)
Affinity DataEC50:  34.3nMAssay Description:Agonist activity at muscarinic M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263888(Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl...)
Affinity DataEC50:  113nMAssay Description:Agonist activity at muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263888(Ethyl 4-(2-oxo-2,3-dihydro-1Hbenzo[d]imidazol-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed