BDBM50264010 6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)pyridazin-3(2H)-one::CHEMBL490613

SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2nc(ccc2=O)-n2ccc3ccccc23)CC1

InChI Key InChIKey=MKHSUBPUHSIMQZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264010   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264010(6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264010(6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]ketanserine from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264010(6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed