BDBM50264131 CHEMBL522969::N-(4-Chloro-2-fluorophenyl)-1-(3-chloropyridin-2-yl)-1,2,3,6-tetrahydropyridine-4-carboxamide

SMILES Fc1cc(Cl)ccc1NC(=O)C1=CCN(CC1)c1ncccc1Cl

InChI Key InChIKey=MLDQSQZWOMTCER-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264131   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50264131(N-(4-Chloro-2-fluorophenyl)-1-(3-chloropyridin-2-y...)Copy SMILESCopy InChI

Affinity DataIC50: 618nMAssay Description:Antagonist activity at human recombinant TRPV1 expressed in human 1321N1 cells assessed as inhibition of capsaicin-induced calcium influx by FLIPR as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL