BDBM50264748 (R)-2-(6-(1-(2-hydroxy-3-methoxypropyl)-1H-pyrazol-4-yl)-2H-benzo[b][1,4]oxazin-4(3H)-yl)-6,6-dimethyl-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one::CHEMBL489602

SMILES COC[C@H](O)Cn1cc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1

InChI Key InChIKey=DDNDFDDGMCJGHM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264748   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Ucb Pharma

Curated by ChEMBL

LigandBDBM50264748((R)-2-(6-(1-(2-hydroxy-3-methoxypropyl)-1H-pyrazol...)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Ucb Pharma

Curated by ChEMBL

LigandBDBM50264748((R)-2-(6-(1-(2-hydroxy-3-methoxypropyl)-1H-pyrazol...)Copy SMILESCopy InChI

Affinity DataIC50: 51nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL