BDBM50264768 CHEMBL4079170

SMILES Cc1cc2C(OC3(CCN(CC3)c3ccc(cn3)-c3nc4cc(ccc4[nH]3)C(F)(F)F)c2cc1Cl)C(C)(C)C#N

InChI Key InChIKey=OCWFDZQDNZGZPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264768   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50264768(CHEMBL4079170)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human DGAT1 expressed in yeast membrane fraction assessed as inhibition of triglyceride formation using diolein/oleoyl-CoA as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2020
Entry Details Article
PubMed