BDBM50264780 CHEMBL4067662

SMILES CS(=O)(=O)N1CC2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)c2ccccc21

InChI Key InChIKey=SYSATCXGWFAQTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264780   

TargetDiacylglycerol O-acyltransferase 1(Human)
University of Leeds

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264780BDBM50264780(CHEMBL4067662)
Affinity DataIC50: 68nMAssay Description:Inhibition of DGAT1 (unknown origin) by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
University of Leeds

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264780BDBM50264780(CHEMBL4067662)
Affinity DataIC50: 68nMAssay Description:Inhibition of human DGAT1 expressed in yeast membrane fraction assessed as inhibition of triglyceride formation using diolein/oleoyl-CoA as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2020
Entry Details Article
PubMed