BDBM50264822 CHEMBL4091946

SMILES O=C(O)c1ccc2c(c1)C(=O)OC21CCN(c2ccc(-c3nc4cc(C(F)(F)F)ccc4[nH]3)cn2)CC1

InChI Key InChIKey=YYEOGOCGDPAYFM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264822   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50264822(CHEMBL4091946)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of human DGAT1 expressed in yeast membrane fraction assessed as inhibition of triglyceride formation using diolein/oleoyl-CoA as substrate...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/6/2020
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50264822(CHEMBL4091946)Copy SMILESCopy InChI

Affinity DataIC50: 560nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/6/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL