BDBM50264873 6,6-dimethyl-2-(6-(6-phenylpyridazin-3-ylamino)-2H-benzo[b][1,4]oxazin-4(3H)-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one::CHEMBL496940

SMILES CC1(C)Cc2nc(sc2C(=O)N1)N1CCOc2ccc(Nc3ccc(nn3)-c3ccccc3)cc12

InChI Key InChIKey=XGTSXSXOYSMLKN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264873   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Ucb Pharma

Curated by ChEMBL

LigandBDBM50264873(6,6-dimethyl-2-(6-(6-phenylpyridazin-3-ylamino)-2H...)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Ucb Pharma

Curated by ChEMBL

LigandBDBM50264873(6,6-dimethyl-2-(6-(6-phenylpyridazin-3-ylamino)-2H...)Copy SMILESCopy InChI

Affinity DataIC50: 34nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL