BDBM50265069 CHEMBL497350::N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-yl)-4-((4-methylpiperazin-1-yl)methyl)benzamide

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(c2)-c2ccc(cc2C)-c2nnc(C)o2)CC1

InChI Key InChIKey=HSCYIVKNKNXHIF-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50265069   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265069(N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed