BDBM50265085 (+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin-3-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide::CHEMBL495718

SMILES CSc1ccc(CNC2CCNCC2NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=SAQHQBAGPCZQKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265085   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265085((+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin...)
Affinity DataIC50: 97nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265085((+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin...)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed