BDBM50265204 (+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benzamido)piperidin-3-ylamino)-2-oxoethyl)-5-(trifluoromethyl)benzamide::CHEMBL496343

SMILES CSc1ccc(cc1)C(=O)NC1CCN(C)CC1NC(=O)CNC(=O)c1cc(ccc1N)C(F)(F)F

InChI Key InChIKey=JZTKKQOTCBZVAE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265204   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 38.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed