BDBM50265257 CHEMBL498390::N-(4-methyl-3-(1-oxo-1,2-dihydroisoquinolin-7-yl)phenyl)-2-(pyrrolidin-1-yl)isonicotinamide

SMILES Cc1ccc(NC(=O)c2ccnc(c2)N2CCCC2)cc1-c1ccc2cc[nH]c(=O)c2c1

InChI Key InChIKey=XNDBJDASTBQWJM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265257   

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265257(N-(4-methyl-3-(1-oxo-1,2-dihydroisoquinolin-7-yl)p...)
Affinity DataKi:  2.40nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed