BDBM50265640 4-Amino-3-[5-(2-morpholin-4-ylethoxy)-benzimidazol-2-yl]hydroquinolin-2-one::CHEMBL526658

SMILES Nc1c(-c2nc3ccc(OCCN4CCOCC4)cc3[nH]2)c(=O)[nH]c2ccccc12

InChI Key InChIKey=MVKVCQNFFRDQDJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265640   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265640(4-Amino-3-[5-(2-morpholin-4-ylethoxy)-benzimidazol...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265640(4-Amino-3-[5-(2-morpholin-4-ylethoxy)-benzimidazol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265640(4-Amino-3-[5-(2-morpholin-4-ylethoxy)-benzimidazol...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed