BDBM50265815 CHEMBL4065064

SMILES Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CCC3=Cc12)S(=O)(=O)c1ccc(Cl)c(Cl)c1)C(=O)c1nccs1

InChI Key InChIKey=AURKEGXHQRGHFD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265815   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50265815(CHEMBL4065064)
Affinity DataKi:  0.590nMAssay Description:Displacement of fluormone GS Red from human glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50265815(CHEMBL4065064)
Affinity DataKi:  16nMAssay Description:Antagonist activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of dexamethasone-induced tyrosine amino transferase activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed