BDBM50265939 CHEMBL4078489
SMILES OC[C@@H](N1CCc2[nH]c(cc2C1=O)-c1ccnc(NC2CCOCC2)n1)c1ccccc1
InChI Key InChIKey=HRSNHMRHSYFCLY-JOCHJYFZSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50265939
Affinity DataIC50: <0.340nMAssay Description:Inhibition of ERK2 (unknown origin) in the presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated ERK2 levelsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated RSK levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of ERK2 (unknown origin) in the presence of 1 mM ATPMore data for this Ligand-Target Pair