BDBM50265971 CHEMBL4087393
SMILES COCCN1[C@@H](C)Cc2[nH]c(cc2C1=O)-c1nc(Nc2ccnn2C)ncc1C
InChI Key InChIKey=PNXHDOWDWLRBSB-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50265971
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated ERK2 levelsMore data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMAssay Description:Inhibition of ERK2 (unknown origin) in the presence of 1 mM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMAssay Description:Inhibition of ERK2 (unknown origin) in the presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated RSK levelsMore data for this Ligand-Target Pair