BDBM50266016 5-(3,5-di-tert-butyl-4-methoxyphenyl)-3H-1,2-dithiole-3-thione::CHEMBL462709

SMILES COc1c(cc(cc1C(C)(C)C)-c1cc(=S)ss1)C(C)(C)C

InChI Key InChIKey=ADYCDQRKYSUEAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266016   

TargetProstaglandin G/H synthase 2(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50266016(5-(3,5-di-tert-butyl-4-methoxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50266016(5-(3,5-di-tert-butyl-4-methoxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human platelet COX1 assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed