BDBM50266056 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)propanamide::CHEMBL459280

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CNC1=O

InChI Key InChIKey=QBXKIGHVYCRJPK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266056   

TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266056((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266056((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S...)
Affinity DataKi:  368nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266056((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S...)
Affinity DataIC50: 631nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig assessed as inhibition of electrically evoked ileum contraction by GPI testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed