BDBM50266057 (S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)propanamide::CHEMBL459281

SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N[C@H]1Cc2ccccc2CNC1=O

InChI Key InChIKey=XNYZNBPSFSIZKH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266057   

TargetDelta-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266057((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphe...)
Affinity DataKi:  20.5nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266057((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphe...)
Affinity DataKi:  64.9nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266057((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig assessed as inhibition of electrically evoked ileum contraction by GPI testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266057((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse assessed as inhibition of electrically evoked vas-deferens contraction by MVD testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed