BDBM50266060 (S)-2-amino-N-((R)-2-(2-(benzylamino)-2-oxoethyl)-3-oxo-1,2,3,4,5,10-hexahydroazepino[3,4-b]indol-4-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL506761

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1Cc2c(CN(CC(=O)NCc3ccccc3)C1=O)[nH]c1ccccc21

InChI Key InChIKey=DGSVUCDQWMCAPS-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266060   

TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266060((S)-2-amino-N-((R)-2-(2-(benzylamino)-2-oxoethyl)-...)
Affinity DataKi:  3.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266060((S)-2-amino-N-((R)-2-(2-(benzylamino)-2-oxoethyl)-...)
Affinity DataIC50: 14.9nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig assessed as inhibition of electrically evoked ileum contraction by GPI testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266060((S)-2-amino-N-((R)-2-(2-(benzylamino)-2-oxoethyl)-...)
Affinity DataKi:  161nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in Sprague-Dawley rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50266060((S)-2-amino-N-((R)-2-(2-(benzylamino)-2-oxoethyl)-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse assessed as inhibition of electrically evoked vas-deferens contraction by MVD testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed