BDBM50266295 2-(2-(4-(4-isobutylpiperazin-1-yl)-2-methoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzonitrile::CHEMBL514577

SMILES COc1cc(ccc1Nc1nc(Nc2ccccc2C#N)c2cc[nH]c2n1)N1CCN(CC(C)C)CC1

InChI Key InChIKey=HUMUNFMWVZIXCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266295   

TargetInsulin-like growth factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266295(2-(2-(4-(4-isobutylpiperazin-1-yl)-2-methoxyphenyl...)
Affinity DataIC50: 79nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266295(2-(2-(4-(4-isobutylpiperazin-1-yl)-2-methoxyphenyl...)
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of IGF1R phosphorylation by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed