BDBM50266296 CHEMBL456269::N2-(4-(4-isopropylpiperazin-1-yl)-2-methoxyphenyl)-N4-(2-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES COc1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(CC2)C(C)C)nc2[nH]ccc12

InChI Key InChIKey=MZBYDNPCLRZMRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266296   

TargetInsulin-like growth factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266296(N2-(4-(4-isopropylpiperazin-1-yl)-2-methoxyphenyl)...)
Affinity DataIC50: 32nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266296(N2-(4-(4-isopropylpiperazin-1-yl)-2-methoxyphenyl)...)
Affinity DataIC50: 982nMAssay Description:Inhibition of IGF1R phosphorylation by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed