BDBM50267010 CHEMBL4082395
SMILES COc1ccc(F)c(c1)-c1ccc(Cc2ccc(cc2)N2C[C@H](C[C@H]2CC(O)=O)C(F)(F)F)c(C)c1
InChI Key InChIKey=PKUNNSLPQXPQEP-GMAHTHKFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50267010
Affinity DataKi: 45nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as induction of cAMP accumulation incubated for 30 to 45 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as induction of cAMP accumulation incubated for 30 to 45 mins by HTRF assayMore data for this Ligand-Target Pair