BDBM50267069 4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminothiazolidin-3-yl]methyl}benzoic acid::CHEMBL478274

SMILES OC(=O)c1ccc(CN2\C(S\C(=C/c3ccc(Oc4ccccc4)cc3)C2=O)=N\c2ccccc2)cc1

InChI Key InChIKey=OUAHCPZNWTVQRU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267069   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267069(4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267069(4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Baker's yeast)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267069(4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae Ltp1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267069(4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed