BDBM50267141 4-[5-(3-Hydroxy-4-methoxybenzylidene)-4-oxo-2-phenyliminothiazolidin-3-ylmethyl]benzoic acid::CHEMBL514517

SMILES COc1ccc(\C=C2/S\C(=N/c3ccccc3)N(Cc3ccc(cc3)C(O)=O)C2=O)cc1O

InChI Key InChIKey=IZCLPTPCMSVZFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267141   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267141(4-[5-(3-Hydroxy-4-methoxybenzylidene)-4-oxo-2-phen...)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267141(4-[5-(3-Hydroxy-4-methoxybenzylidene)-4-oxo-2-phen...)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Baker's yeast)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267141(4-[5-(3-Hydroxy-4-methoxybenzylidene)-4-oxo-2-phen...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Saccharomyces cerevisiae Ltp1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50267141(4-[5-(3-Hydroxy-4-methoxybenzylidene)-4-oxo-2-phen...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed