BDBM50267477 CHEMBL477666::N6-cyclopentyl-5'-(2-fluorophenylthio)-5'-deoxyadenosine

SMILES O[C@@H]1[C@@H](CSc2ccccc2F)O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12

InChI Key InChIKey=SKEFGDREBIAUKI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267477   

TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267477(N6-cyclopentyl-5'-(2-fluorophenylthio)-5'-deoxyade...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267477(N6-cyclopentyl-5'-(2-fluorophenylthio)-5'-deoxyade...)
Affinity DataKi:  296nMAssay Description:Displacement of [3H]HEMADO from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267477(N6-cyclopentyl-5'-(2-fluorophenylthio)-5'-deoxyade...)
Affinity DataKi:  5.17E+3nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267477(N6-cyclopentyl-5'-(2-fluorophenylthio)-5'-deoxyade...)
Affinity DataKi: >1.00E+4nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed